Opportunity Information: Apply for PA 17 041
The National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) titled "Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R01)" (Funding Opportunity Number: PA-17-041) supports research grant applications that aim to explain why certain immigrant groups in the United States experience worse health outcomes (health disparities) while others show unexpectedly favorable outcomes (health advantages). The focus is on the underlying causes, or etiology, of these patterns. NIH is looking for innovative studies that examine factors that are uniquely tied to immigrant experiences and contexts, including biological influences, behavioral pathways, sociocultural conditions, and environmental exposures. In practice, this means projects can explore how migration histories, settlement contexts, acculturation pressures, discrimination, work and housing conditions, policy environments, family structure, diet and activity changes, stress physiology, and community-level supports or risks interact to shape health over time.
This opportunity uses the R01 mechanism, meaning it is intended for substantial, hypothesis-driven research projects that can produce rigorous, generalizable knowledge. The FOA sits within NIH's broader mission areas spanning health, education, environment, and related determinants, and is associated with multiple CFDA numbers (93.113, 93.121, 93.273, 93.279, 93.307, 93.396, 93.399), reflecting that immigrant health research may align with several NIH institutes and centers depending on the specific disease area, population, or determinant being studied. While the announcement text does not specify an award ceiling or the expected number of awards, it clearly frames the scientific priority: clarifying the mechanisms that create either vulnerability or resilience among immigrant populations in the U.S., rather than simply describing differences.
Eligibility is broad and includes many types of U.S.-based organizations and government entities. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other organizations that meet NIH requirements. The FOA also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal government agencies; regional organizations; U.S. territories or possessions; and Indian/Native American Tribal Governments that are not federally recognized. This emphasis signals an interest in encouraging applications from institutions and organizations that are often closely connected to immigrant communities or that serve populations experiencing health inequities.
At the same time, the FOA draws clear lines around foreign participation. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the primary applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, "foreign components" are allowed as defined by the NIH Grants Policy Statement, meaning a U.S. applicant can include certain types of international involvement when it is scientifically justified and structured in compliance with NIH policy. This can matter for immigrant health research when parts of the research question involve transnational ties, pre-migration exposures, or comparisons that require specific data, expertise, or collaborations outside the U.S., as long as the applicant and project structure meet NIH rules.
Key administrative details in the source information include that the opportunity is categorized as discretionary funding, uses a grant funding instrument, and was created on 2016-11-01. The original closing date listed is 2020-01-07, which indicates the specific submission window referenced in the posting and suggests that applicants should verify whether the FOA is still active, has been reissued, or has transitioned to a newer announcement number before preparing an application. Overall, the FOA is designed to move the field beyond documenting immigrant health patterns toward explaining them, by identifying immigrant-specific drivers of risk and protection across biological, behavioral, sociocultural, and environmental levels.Apply for PA 17 041
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.273, 93.279, 93.307, 93.396, 93.399.
- This funding opportunity was created on 2016-11-01.
- Applicants must submit their applications by 2020-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this NIH announcement?
The Funding Opportunity Announcement (FOA) is titled "Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R01)" and the Funding Opportunity Number is PA-17-041.
What is the main purpose of this FOA?
This FOA supports research grant applications that aim to explain why some immigrant groups in the United States experience worse health outcomes (health disparities) while other immigrant groups show unexpectedly favorable outcomes (health advantages). The emphasis is on identifying underlying causes (etiology) and mechanisms, not simply describing differences.
What does NIH mean by focusing on "etiology" in immigrant health?
In this FOA, etiology refers to the underlying causes and pathways that produce vulnerability or resilience among immigrant populations. Projects are expected to clarify mechanisms that lead to disparities or advantages, rather than only documenting patterns or associations.
What funding mechanism does this opportunity use?
The opportunity uses the NIH R01 mechanism. This is intended for substantial, hypothesis-driven research projects designed to generate rigorous, generalizable knowledge.
What kinds of factors and pathways are NIH interested in for proposed studies?
NIH is interested in innovative studies examining factors uniquely tied to immigrant experiences and contexts. Examples described in the opportunity include biological influences, behavioral pathways, sociocultural conditions, and environmental exposures, as well as how these domains interact over time.
What immigrant-specific topics or contexts are specifically mentioned as relevant?
The opportunity notes that projects may explore topics such as migration histories, settlement contexts, acculturation pressures, discrimination, work and housing conditions, policy environments, family structure, diet and activity changes, stress physiology, and community-level supports or risks, and how these factors interact to shape health over time.
Is this FOA focused on describing immigrant health patterns or explaining them?
It is framed as moving beyond documenting immigrant health patterns toward explaining them. The stated scientific priority is clarifying mechanisms that create vulnerability or resilience among immigrant populations in the U.S.
What types of organizations are eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and government entities. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other organizations that meet NIH requirements.
Are institutions that serve specific communities explicitly encouraged or highlighted as eligible?
Yes. The FOA explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal government agencies; regional organizations; U.S. territories or possessions; and Indian/Native American Tribal Governments that are not federally recognized.
Can foreign (non-U.S.) institutions apply as the main applicant?
No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the primary applicant organization under this FOA.
Can a non-domestic component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are also not eligible to apply as the applicant organization.
Are any types of international involvement allowed?
Yes. "Foreign components" are allowed as defined by the NIH Grants Policy Statement. This means a U.S. applicant may include certain international involvement when scientifically justified and structured to comply with NIH policy.
Why might a foreign component matter for immigrant health research under this FOA?
The FOA notes that foreign components can be relevant when research questions involve transnational ties, pre-migration exposures, or comparisons requiring specific data, expertise, or collaborations outside the U.S., as long as NIH rules are met and the U.S. applicant remains the primary applicant organization.
Does the FOA specify an award ceiling or the expected number of awards?
No. The information provided indicates the announcement text does not specify an award ceiling or the expected number of awards.
Which CFDA numbers are associated with this opportunity?
The FOA is associated with multiple CFDA numbers: 93.113, 93.121, 93.273, 93.279, 93.307, 93.396, and 93.399.
Why are multiple CFDA numbers associated with this FOA?
The multiple CFDA numbers reflect that immigrant health research may align with several NIH institutes and centers depending on the specific disease area, population, or determinant being studied.
What type of funding is this categorized as?
The opportunity is categorized as discretionary funding.
What is the funding instrument for this opportunity?
The funding instrument is a grant.
When was this opportunity created?
The source information indicates the opportunity was created on 2016-11-01.
What is the closing date listed in the provided information?
The original closing date listed is 2020-01-07.
Should applicants verify whether the FOA is still active?
Yes. Because the provided closing date is 2020-01-07, applicants are advised (based on the source information) to verify whether the FOA is still active, has been reissued, or has transitioned to a newer announcement number before preparing an application.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 17 041) also looked into and applied for these:
| Funding Opportunity |
|---|
| Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R21) Apply for PA 17 042 Funding Number: PA 17 042 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R21) Apply for PA 17 044 Funding Number: PA 17 044 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Expanding Genome Integrity Assays to Population Studies (U01) Apply for RFA ES 17 006 Funding Number: RFA ES 17 006 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $400,000 |
| Ethical, Legal, and Social Implications (ELSI) of Genomics Small Research Grant Program (R03) Apply for PA 17 324 Funding Number: PA 17 324 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $50,000 |
| Ethical, Legal, and Social Implications (ELSI) of Genomics Exploratory/Developmental Research Grant Program (R21) Apply for PA 17 323 Funding Number: PA 17 323 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $275,000 |
| Ethical, Legal, and Social Implications (ELSI) of Genomics Research Project Grant Program (R01) Apply for PA 17 325 Funding Number: PA 17 325 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Administrative Supplements for the U.S.-Japan Brain Research Cooperative Program (BRCP) - U.S. Entity (Admin Supplement) Apply for PA 17 326 Funding Number: PA 17 326 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R01 - Clinical Trial Not Allowed) Apply for PAR 17 476 Funding Number: PAR 17 476 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R21 - Clinical Trial Not Allowed) Apply for PAR 17 475 Funding Number: PAR 17 475 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Collaborative Minority Health and Health Disparities Research with Tribal Epidemiology Centers (R01) Apply for PAR 17 484 Funding Number: PAR 17 484 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $350,000 |
| Collaborative Minority Health and Health Disparities Research with Tribal Epidemiology Centers (R21) Apply for PAR 17 483 Funding Number: PAR 17 483 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Research to Improve Native American Health (R21 Clinical Trial Optional) Apply for PAR 17 464 Funding Number: PAR 17 464 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) Apply for PAR 17 496 Funding Number: PAR 17 496 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R01 Clinical Trial Optional) Apply for PA 18 284 Funding Number: PA 18 284 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R21 Clinical Trial Optional) Apply for PA 18 285 Funding Number: PA 18 285 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| NIH Research Project Grant (Parent R01 Clinical Trial Required) Apply for PA 18 345 Funding Number: PA 18 345 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Research to Action: Assessing and Addressing Community Exposures to Environmental Contaminants (R01 Clinical Trial Optional) Apply for PA 18 260 Funding Number: PA 18 260 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required) Apply for PA 18 344 Funding Number: PA 18 344 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21 Clinical Trial Optional) Apply for PA 18 160 Funding Number: PA 18 160 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01 Clinical Trial Optional) Apply for PA 18 142 Funding Number: PA 18 142 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
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